A multiprocessor data processing system includes a processor core having a translation structure for buffering a plurality of translation entries. In response to receipt of a translation invalidation request, the processor core determines from the translation invalidation request that the translation invalidation request does not require draining of memory referent instructions for which address translation has been performed by reference to a translation entry to be invalidated. Based on the determination, the processor core invalidates the translation entry in the translation structure and confirms completion of invalidation of the translation entry without regard to draining from the processor core of memory access requests for which address translation was performed by reference to the translation entry.