A motherboard includes a multilayer printed circuit board (PCB), a central processing unit (CPU) slot, at least one first memory slot, at least one second memory slot, a plurality of first traces, and a plurality of second traces. The CPU slot, the first memory slot, and the second memory slot are disposed on the first wiring layer of the multilayer PCB, and the second memory slot is disposed between the first memory slot and the CPU slot. The first traces are disposed on the first wiring layer of the multilayer PCB. The CPU slot is electrically connected to the first memory slot by the first traces. The second traces are disposed on the second wiring layer of the multilayer PCB which is different from the first wiring layer, and the CPU slot is electrically connected with the second memory slot by the second traces.