A dialog generation method, apparatus, and device, and a storage medium are provided. The method includes converting each term in a Kth round of a query sentence into a first word vector, and calculating a positive latent vector and a negative latent vector of each term according to the first word vector, where K denotes a positive integer greater than or equal to 2. A content topic of the Kth round of the query sentence is obtained, and converted into a second word vector. An initial latent vector output for the Kth round of the query sentence is determined according to the second word vector, the positive latent vector of a last term in the Kth round of the query sentence, a latent vector of a last term in a (K-1)th round of a reply sentence output for a (K-1)th round of the query sentence, and an initial latent vector of the (K-1)th round of the reply sentence output for the (K-1)th round of the query sentence. A reply sentence for the Kth round of the query sentence is generated according to the positive latent vector and the negative latent vector of each term in the Kth round of the query sentence and the initial latent vector output for the Kth round of the query sentence.