A computer-implemented method of performing machine vision prediction of digital images using synthetically generated training assets comprises digitally capturing a plurality of assets; configuring each of the assets in the plurality of assets with a plurality of asset attributes; under computer program control, selecting a plurality of different combinations of parameters from among the plurality of asset attributes, and creating a plurality of sets of different synthetic dataset parameters; using computer graphics software, and example parameter values from among the synthetic dataset parameters, creating a synthetic dataset by compiling from a plurality of example images and metadata; configuring a plurality of machine learning trials and executing the trials to train a machine vision model, resulting in creating and storing a trained machine vision model; executing a validation of the trained machine vision model; and inferring a prediction using the trained machine vision model. Trained models are scored against success criteria and re-trained using pseudo-random sampling of different parameters clustered around failure points. As a result, machine vision models may be trained with high accuracy using large datasets of synthesized digital images that are richly parameterized, rather than human captured digital images.