The disclosure is directed to maintaining an asynchronous communication via an intermediary. An agent executed on a device intermediary to clients and providers can receive a request from a client for an asynchronous communication between the client device and a provider device. The agent identifies a provider dynamic identifier identifying the provider. The agent uses a communication channel selection policy to determine a communication channel and a provider static identifier corresponding to the provider device. The agent maps a client dynamic identifier assigned by the server to a client static identifier of the client device. The agent generates a transmission data package including the content, a source address identifying the client dynamic identifier and a destination address identifying the provider static identifier. The agent provides the generated transmission data package for transmission via the communication channel determined using the communication channel selection policy to the provider device.