An electric surgical stapler including a handle and a working head. The handle has a handle body, a driving motor, and a control unit for controlling the driving motor to operate. The working head includes an anvil, a cartridge, a closing mechanism, a firing mechanism, a housing for accommodating the closing mechanism and the firing mechanism, a closing limit switch configured to transmit information of a closing stroke of the closing mechanism to the control unit, and a pressure sensor configured to transmit a pressure value applied to a squeezed tissue during closing to the control unit. The control unit is configured to transmit an instruction of controlling the driving motor to drive movement of the firing mechanism, when the closing limit switch is triggered and the pressure value transmitted by the pressure sensor meets a preset standard.