Invention Grant
- Patent Title: Compound for anti-cancer therapy that acts by targeting GOF mutant p53 and stimulates p73 to restore the p53 pathway signaling
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Application No.: US16396829Application Date: 2019-04-29
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Publication No.: US10744133B2Publication Date: 2020-08-18
- Inventor: Wafik S. El-Deiry , Shengliang Zhang
- Applicant: The Penn State Research Foundation
- Applicant Address: US PA University Park
- Assignee: The Penn State Research Foundation
- Current Assignee: The Penn State Research Foundation
- Current Assignee Address: US PA University Park
- Agency: Riverside Law LLP
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D307/71
Abstract:
The invention includes compositions comprising NSC59984 or a derivative or analogue thereof and a pharmaceutically acceptable carrier. The invention further includes methods of treating or preventing cancer in a subject, comprising the step of administering to the subject the compositions contemplated within the invention.
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