- Patent Title: Imidazolonylquinolines and the use thereof as ATM kinase inhibitors
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Application No.: US16353559Application Date: 2019-03-14
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Publication No.: US10745399B2Publication Date: 2020-08-18
- Inventor: Thomas Fuchss , Kai Schiemann
- Applicant: Merck Patent GmbH
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen White Zelano and Branigan, PC
- Agent Csaba Henter
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@dbd291a
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P35/00 ; A61K31/4375 ; A61K45/06 ; C07D519/00

Abstract:
A compound of formula (IV) or a pharmaceutically acceptable salt, solvate, tautomer or stereoisomer thereof These imidazolonylquinoline compounds are useful in the inhibition, regulation and/or modulation of signal transduction by kinases, in particular ATM kinase, furthermore in pharmaceutical compositions, and in their use for the treatment of diseases which relate to ATM kinase, in particular cancer.
Public/Granted literature
- US20190211013A1 IMIDAZOLONYLQUINOLINES AND THE USE THEREOF AS ATM KINASE INHIBITORS Public/Granted day:2019-07-11
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