Invention Grant
- Patent Title: Ultra-pure agonists of guanylate cyclase C, method of making and using same
-
Application No.: US16000251Application Date: 2018-06-05
-
Publication No.: US10745441B2Publication Date: 2020-08-18
- Inventor: Kunwar Shailubhai , Stephen Comiskey , Rong Feng , Juncai Bai , Ruoping Zhang , Jun Jia , Junfeng Zhou , Qiao Zhao , Guoqing Zhang
- Applicant: Bausch Health Ireland Limited
- Applicant Address: IE Dublin
- Assignee: Bausch Health Ireland Limited
- Current Assignee: Bausch Health Ireland Limited
- Current Assignee Address: IE Dublin
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Domingos J. Silva; Dennis Ostrovsky
- Main IPC: C07K1/14
- IPC: C07K1/14 ; C07K7/08 ; C12N9/88 ; B01D15/42
Abstract:
The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.
Public/Granted literature
- US20190002501A1 ULTRA-PURE AGONISTS OF GUANYLATE CYCLASE C, METHOD OF MAKING AND USING SAME Public/Granted day:2019-01-03
Information query
