Invention Grant
- Patent Title: Endothelin-1 receptor based endothelin-1 sponge
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Application No.: US16039655Application Date: 2018-07-19
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Publication No.: US10745455B2Publication Date: 2020-08-18
- Inventor: Arjun Jain
- Applicant: Arjun Jain
- Agency: Browdy and Neimark, PLLC
- Main IPC: C07K16/46
- IPC: C07K16/46 ; C12N15/00 ; C07K14/00 ; A61K38/00 ; C07K14/575 ; C07K14/72 ; A61P9/10 ; A61P25/28 ; A61P3/10 ; A61K47/00 ; C07K14/735 ; C12N15/113 ; C12N15/62 ; A61K38/16
Abstract:
Fusion polypeptides capable of binding endothelin-1 to form a non-functional complex are provided, including amino acid sequences of the fusion polypeptides. The fusion polypeptides will be linked to the Fe portion of human IgG I to form dimers that will function as endothelin-1 antagonists (endothelin-1 sponge).
Public/Granted literature
- US20190016773A1 ENDOTHELIN-1 RECEPTOR BASED ENDOTHELIN-1 SPONGE Public/Granted day:2019-01-17
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