Invention Grant
- Patent Title: Anti-NOTCH3 antibodies
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Application No.: US15864710Application Date: 2018-01-08
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Publication No.: US10745476B2Publication Date: 2020-08-18
- Inventor: Heidi Okamura , Sandra Abbott , Alisa C. Bell , Kelly Kreuter , Ronan O'Hagan , Samantha Perino , Hamid Tissire , William M. Winston, Jr. , Jeno Gyuris
- Applicant: AVEO Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K16/28 ; A61K39/395 ; C12N15/09 ; C12N15/63 ; C12N5/10 ; C12N5/12 ; C12N5/16 ; A61K39/00
Abstract:
Monoclonal antibodies that bind and inhibit activation of human Notch3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of Notch3.
Public/Granted literature
- US20180230213A1 ANTI-NOTCH3 ANTIBODIES Public/Granted day:2018-08-16
Information query
