Systems and methods for identifying a likelihood that a reservoir of a geological formation received a secondary charge of hydrocarbons of relatively very different thermal maturity of composition are provided. One method includes positioning a downhole acquisition tool in a wellbore in a geological formation and testing one or more fluid properties of the formation fluid. Data processing circuitry may identify whether a relationship of the one or more fluid properties exceeds a first threshold that indicates likely asphaltene instability. When this is the case, data processing circuitry may be used to model the geological formation using a realization scenario in which multiple charges of hydrocarbons of substantially different thermal maturity or substantially different composition, or both, filled a reservoir of the geological formation over geologic time.