Invention Grant
- Patent Title: Method for the enrichment of cell free nucleosomes
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Application No.: US15768984Application Date: 2016-10-21
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Publication No.: US10746746B2Publication Date: 2020-08-18
- Inventor: Mark Edward Eccleston , Jacob Vincent Micallef
- Applicant: BELGIAN VOLITION SPRL
- Applicant Address: BE Isnes
- Assignee: Belgian Volition SPRL
- Current Assignee: Belgian Volition SPRL
- Current Assignee Address: BE Isnes
- Agency: McDermott, Will & Emery LLP
- Agent Judy M. Mohr
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7b0c75f0
- International Application: PCT/GB2016/053305 WO 20161021
- International Announcement: WO2017/068371 WO 20170427
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/574 ; G01N33/53 ; C12Q1/6886
Abstract:
The present invention relates to the use of a histone H1 binding agent for detecting, isolating and/or purifying cell free nucleosomes of tumor origin from a biological sample. The invention also describes methods of negative or positive selection using histone H1 binding agents, in order to enrich a sample for cell free nucleosomes of tumor origin.
Public/Granted literature
- US20190064184A1 METHOD FOR THE ENRICHMENT OF CELL FREE NUCLEOSOMES Public/Granted day:2019-02-28
Information query
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