Described herein are systems and methods for a virtual communication and collaboration application platform which automates the setup and operation of a virtual collaboration session, senses and reacts to user activity and contextual cues, and provides real-time intuitive interaction steps to enable users to easily interact in a simple and user-friendly manner. The Virtual Collaboration and Computing Platform provides a shared application window visible to multiple users on different displays for which users can easily share multiple types of data and applications through basic drag-and-drop interactions.