Invention Grant
- Patent Title: Techniques for determining whether an individual is included in ensemble genomic data
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Application No.: US15766611Application Date: 2016-10-06
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Publication No.: US10747899B2Publication Date: 2020-08-18
- Inventor: Suyash Shringarpure , Carlos D. Bustamante
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Palo Alto
- Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Current Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Current Assignee Address: US CA Palo Alto
- Agency: Beusse Wolter Sanks & Maire
- Agent Eugene J. Molinelli
- International Application: PCT/US2016/055717 WO 20161006
- International Announcement: WO2017/062599 WO 20170413
- Main IPC: G06F21/62
- IPC: G06F21/62 ; G06F16/00 ; G06F16/903 ; G16B20/00 ; G16B50/00 ; G16B20/40 ; G16H10/60

Abstract:
Techniques to determine if an individual is a member of an ensemble contributing to combined genomic data include determining a site frequency spectrum (SFS) for alleles in the combined genomic data, and a number N of individuals contributing to the combined genomic data. Based on the SFS and N, both a number of queries NQ and a number of yeses NY are determined. NY is a number of yes responses to NQ queries, which indicates a particular likelihood that the individual is a member of the ensemble. Output is based on at least one of NQ and NY. For example, fewer than NQ queries from a single source are answered from a beacon. Alternatively, the likelihood that an individual is a member of the ensemble is determined based on responses to NQ queries about NQ different alleles present in the individual and NY.
Public/Granted literature
- US20180285593A1 Techniques for Determining Whether an Individual Is Included in Ensemble Genomic Data Public/Granted day:2018-10-04
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