A display panel and a method of driving the display panel are proposed. The display panel includes a pixel array, a data driving circuit comprising one or more data line, a scanning driving circuit, and a demultiplexing circuit. The scanning driving circuit and the demultiplexing circuit both are configured to input a data signal through the data line into the first subpixel, the second subpixel, the fourth subpixel, and the third subpixel sequentially. The present disclosure can reduce power consumption of the display panel.