Presented herein are techniques for suppressing electrical interference caused by a feedback path(s) between an output channel and an input channel of an implantable medical device. In particular, the output channel carries stimulation signals that can pass through the feedback path(s) and appear in the input channel, thereby causing interference with any input signals carried by the input channel. The implantable medical device is configured to determine characteristics of the feedback and subsequently use the feedback characteristics to generate feedback compensation signals for application to the input channel.