The present invention is directed to a nanostructured binary oxide TiO2—Al2O3 with high acidity and its synthesis process via the sol-gel method, hydrotreating and thermal activation. The nanostructured binary oxide TiO2—Al2O3 with high acidity consists basically of titanium oxide and aluminum oxide with the special characteristic of being obtained as nanostructures, in their nanocrystal-nanotube evolution, which provides special physicochemical properties such as high specific area, purity and phase stability, acidity stability and different types of active acid sites, in addition to the capacity to disperse and stabilize active metal particles with high activity and selectivity mainly in catalytic processes.