In personalized object creation, for implants, medical imaging is used to derive a model personalized to a patient. The model may be of a dynamic structure, such as part of the cardiovascular system, and is used to print the implant itself. The model may be used to print a mold to create the implant, a scaffold on which to grow tissue, and/or tissue itself. In another or additional approach, the medical imaging information is used to determine tissue properties. Differences in a material property of the anatomy is mapped to different materials used by a multi-material 3D printer, resulting in a printed object reflecting the size, shape, and/or other material property of the anatomy of the patient.