A sealing system for connecting a bulk bag to a material handling and processing system. The sealing system comprises a main housing and a discharge tube housed within the main housing. The discharge tube is configured to fluidly connect the bulk bag with the material handling and processing system. The sealing system additionally comprises a first seal configured to selectively seal the bulk bag with respect to the discharge tube, and a second seal configured to selectively seal an interior space of the main housing from the material handling and processing system.