- Patent Title: Biocompatible nanoparticles with aggregation induced emission characteristics as fluorescent bioprobes and methods of using the same for in vitro and in vivo imaging
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Application No.: US14342074Application Date: 2012-09-03
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Publication No.: US10753941B2Publication Date: 2020-08-25
- Inventor: Benzhong Tang , Wei Qin , Jianzhao Liu , Sijie Chen , Tsz Kin Kwok , Bin Liu , Kai Li , Dan Ding , Haibin Shi , Jun Long Geng , Jingzhi Sun , Anjun Qin , Qiuli Zhao
- Applicant: Benzhong Tang , Wei Qin , Jianzhao Liu , Sijie Chen , Tsz Kin Kwok , Bin Liu , Kai Li , Dan Ding , Haibin Shi , Jun Long Geng , Jingzhi Sun , Anjun Qin , Qiuli Zhao
- Applicant Address: CN Hong Kong SG Singapore
- Assignee: The Hong Kong University of Science and Technology,National University of Singapore
- Current Assignee: The Hong Kong University of Science and Technology,National University of Singapore
- Current Assignee Address: CN Hong Kong SG Singapore
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- International Application: PCT/CN2012/001227 WO 20120903
- International Announcement: WO2013/029340 WO 20130307
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61B8/00 ; A61B10/00 ; G01N33/58 ; A61K49/00 ; C09K11/06 ; C12Q1/37 ; G01N33/574
Abstract:
The development of fluorescent bioprobes comprising organic fluorescent compounds that exhibit aggregation induced emission (AIE) properties, methods of producing the same, and their practical applications for in vitro and in vivo bioimaging.
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