An improved system on a transit vehicle is described for coordinated mediation action in response to an identified environmental anomaly on a shipping container transported by the vehicle. The system has wirelessly broadcasting ID nodes at different locations within the container, and a fire suppression system on the vehicle having a wireless transceiver-based controller operating as a master node that can cause the suppression system to deliver fire suppressant material to the container using a delivery nozzle and pump. The controller, as master node, is configured to operate as a primary monitor for the anomaly by being operative to monitor ID node signals; identify the anomaly based on the signals; generate a layered alert notification related to the anomaly (identifying a targeted mediation action and establishes a mediation response priority); and initiate a mediation response by the suppression system related to the targeted mediation action and the mediation response priority.