A computer-assisted method to timely provide notifications of treatments, the method including receiving de-identified longitudinal medical records, receiving notification data, identifying anonymized patients that received the treatment, identifying notifications for the treatment that were received by the recipients, determining, for each of the identified notifications, whether the recipient is an anonymized patient identified as having received the treatment, determining, for each of the identified notifications for the treatment determined to be received by a recipient that is an anonymized patient identified as having received the treatment, a time relationship between the time when the treatment was received by the anonymized patient and the time that the notification was received by the recipient that is the anonymized patient, and determining, for each of the anonymized patients that received the treatment, associations between one or more time relationships for notifications received by the anonymized patient.