A sole structure for an article of footwear comprises a midsole including a first cushioning layer, a second cushioning layer, and a third cushioning layer. The first cushioning layer has a central portion, and a peripheral portion surrounding the central portion. The first cushioning layer, the second cushioning layer, and the third cushioning layer are stacked with the second cushioning layer directly overlying the peripheral portion of the first cushioning layer, and the third cushioning layer overlying the second cushioning layer and directly overlying the central portion of the first cushioning layer. The first cushioning layer has a domed lower surface extending away from the second cushioning layer and the third cushioning layer and substantially centered under the central portion.