Invention Grant
- Patent Title: Methods and apparatus for neuromodulation
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Application No.: US16571845Application Date: 2019-09-16
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Publication No.: US10758175B2Publication Date: 2020-09-01
- Inventor: Nir Grossman , David Wang , Edward Boyden
- Applicant: Massachusetts Institute of Technology , NuVu LLC
- Applicant Address: US MA Cambridge US MA Cambridge
- Assignee: Massachusetts Institute of Technology,NuVu LLC
- Current Assignee: Massachusetts Institute of Technology,NuVu LLC
- Current Assignee Address: US MA Cambridge US MA Cambridge
- Agent Stephen R. Otis
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61B5/0476 ; G06F17/14 ; A61B5/04 ; A61B5/11 ; A61N5/06 ; A61N7/00

Abstract:
A neuromodulator accurately measures—in real time and over a range of frequencies—the instantaneous phase and amplitude of a natural signal. For example, the natural signal may be an electrical signal produced by neural tissue, or a motion such as a muscle tremor. The neuromodulator generates signals that are precisely timed relative to the phase of the natural signal. For example, the neuromodulator may generate an exogenous signal that is phase-locked with the natural signal. Or, for example, the neuromodulator may generate an exogenous signal that comprises short bursts which occur only during a narrow phase range of each period of an oscillating natural signal. The neuromodulator corrects distortions due to Gibbs phenomenon. In some cases, the neuromodulator does so by applying a causal filter to a discrete Fourier transform in the frequency domain, prior to taking an inverse discrete Fourier transform.
Public/Granted literature
- US20200008743A1 Methods and Apparatus for Neuromodulation Public/Granted day:2020-01-09
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