A powered orthotic device for use with a limb having at least two joints includes at least two brace sub-assemblies. The first brace sub-assembly includes a first powered actuator assembly that receives a first sensor signal from an electromyographic sensor. The first powered actuator assembly applies a first force for driving sections positioned with respect to a first joint to move relative to one another. The second brace sub-assembly includes a second powered actuator assembly that is configured to receive a second sensor signal from a sensor selected from a group consisting of an electromyographic sensor, an inertial measurement unit, and combinations thereof. The second powered actuator assembly applies a second force for driving sections positioned with respect to a second joint to move relative to one another. The second force is based on the first sensor signal or the second sensor signal.