According to the present invention, an extract is obtained from the Globularia genus is obtained from a plant of the genus Globularia and is used for a non-therapeutic cosmetic treatment of the skin and/or appendages. Preferably the species is Globularia cordifolia and the extract is obtained by in vitro plant culture. The extract can be used for preventing and/or treating skin ageing by stimulating the reactions of detoxification and cellular regeneration through a hormetic type response, for improving the transparency and radiance of complexion, for preventing or treating sensitive and reactive skins, for preventing or treating rednesses, for preventing protein glycation, for increasing and/or maintaining the number of dermal stem cells, for increasing and/or maintaining the dermal macromolecules, in particular collagen and elastin, for increasing the volume of the dermis, for preventing and/or treating fines lines and wrinkles, for firming skin, for preventing hair loss and/or stimulating hair regrowth. The invention is also drawn to a method of obtaining the extract by in vitro plant culture of undifferentiated cells of Globularia and an extract of plant origin that can be obtained therefrom.