- Patent Title: Compositions and methods for selectively depleting senescent cells
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Application No.: US16057021Application Date: 2018-08-07
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Publication No.: US10758524B2Publication Date: 2020-09-01
- Inventor: Guangrong Zheng , Daohong Zhou , Xingui Liu , Yingying Wang , Jianhui Chang , Wei Feng , Lijian Shao , Yi Luo
- Applicant: BioVentures, LLC
- Applicant Address: US AR Little Rock
- Assignee: BioVentures, LLC
- Current Assignee: BioVentures, LLC
- Current Assignee Address: US AR Little Rock
- Agency: Polsinelli PC
- Main IPC: A61K31/45
- IPC: A61K31/45 ; A61K31/55 ; A61K31/4015 ; A61K31/5377 ; A61K31/4412 ; A61K31/443 ; A61K31/4439 ; A61K31/444 ; A61K31/4545 ; A61K31/635 ; C07D223/10 ; C07D401/06 ; C07D405/06 ; C07D207/38 ; C07D211/88 ; A23L33/10 ; C07D211/76 ; C07D211/96
Abstract:
The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the composition comprises piperlongumine (PL) or derivative thereof. The selective killing of senescent cells may delay aging and/or treat age-related disorders.
Public/Granted literature
- US20180369223A1 COMPOSITIONS AND METHODS FOR SELECTIVELY DEPLETING SENESCENT CELLS Public/Granted day:2018-12-27
Information query
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