Invention Grant
- Patent Title: Antibodies to tumor associated complex N-glycans with terminal GlcNAcβ residues and methods of use thereof
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Application No.: US15744658Application Date: 2016-07-15
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Publication No.: US10758612B2Publication Date: 2020-09-01
- Inventor: Mai Xu
- Applicant: Washington University
- Agency: Polsinelli PC
- International Application: PCT/US2016/042435 WO 20160715
- International Announcement: WO2017/011728 WO 20170119
- Main IPC: A61K39/395
- IPC: A61K39/395 ; G01N33/574 ; C07K16/30 ; C07H5/06 ; C07K16/28

Abstract:
The present disclosure relates to antibodies specific tumor associated complex N-glycans with terminal GlcNAcβ residues and methods for detecting a tumor in a subject. The present disclosure also relates to therapeutic antibodies specific for tumor associated complex N-glycans with terminal GlcNAcβ residues.
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