Invention Grant
- Patent Title: Liquid formulation comprising GM-CSF neutralizing compound
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Application No.: US15922777Application Date: 2018-03-15
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Publication No.: US10758621B2Publication Date: 2020-09-01
- Inventor: Thomas Urbig , Thomas Boehm , Wolfram Steinhilber , Michael Molhoj
- Applicant: Amgen Research (Munich) GmbH , Takeda GmbH
- Applicant Address: DE Munich DE Constance
- Assignee: Amgen Research (Munich) GmbH,Takeda GmbH
- Current Assignee: Amgen Research (Munich) GmbH,Takeda GmbH
- Current Assignee Address: DE Munich DE Constance
- Agency: DLA Piper LLP (US)
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@12c2dd8f
- Main IPC: A61K47/26
- IPC: A61K47/26 ; A61K47/18 ; A61K39/395 ; C07K16/24 ; A61K39/00

Abstract:
The present invention relates to aqueous formulations comprising a compound neutralizing GM-CSF in concentrations of at least about 20 mg/ml, a tonicity modifier and a buffer, wherein the composition is stable. The ingredients of the formulation preferably provide stability to the compound neutralizing GM-CSF in view of long-term storage. In a preferred aspect, the formulation is for use in therapy, preferably for use in the treatment of inflammatory and autoimmune disorders, preferably including allergic and psoriatic disorders, as well as arthritic and asthmatic disorders. Furthermore, a kit comprising the formulation of the invention is provided.
Public/Granted literature
- US20180207278A1 LIQUID FORMULATION COMPRISING GM-CSF NEUTRALIZING COMPOUND Public/Granted day:2018-07-26
Information query
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