- Patent Title: Process for the production of a hybrid structure consisting of coupled silk fibroin microfibers and nanofibers, hybrid structure thus obtained and its use as implantable medical device
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Application No.: US15522397Application Date: 2015-10-27
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Publication No.: US10758641B2Publication Date: 2020-09-01
- Inventor: Antonio Alessandrino
- Applicant: SILK BIOMATERIALS S.R.L.
- Applicant Address: IT Lomazzo
- Assignee: SILK BIOMATERIALS S.R.L.
- Current Assignee: SILK BIOMATERIALS S.R.L.
- Current Assignee Address: IT Lomazzo
- Agency: Troutman Pepper Hamilton Sanders LLP (Rochester)
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@2f7bc1c7
- International Application: PCT/IB2015/058262 WO 20151027
- International Announcement: WO2016/067189 WO 20160506
- Main IPC: A61L27/22
- IPC: A61L27/22 ; A61L27/54 ; A61L27/36

Abstract:
A method is described for the production of hybrid structures formed by the coupling of nanofibrous parts and microfibrous parts made with silk fibroin, possibly hierarchically organized into complex structures comprising more than two of said parts; these hybrid structures are used as implantable biomedical devices with tailored biological, geometrical and structural features, such that they can be adapted to different application requirements in the field of regenerative medicine.
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