A method for setting a thermal comfort state of at least one user of a vehicle, wherein, at a starting time, at least one actual state variable of the user is detected by at least one device for detecting the at least one state variable and a starting comfort state of the user is determined depending on the at least one actual state variable, wherein a target comfort state is determined, wherein at least one target state variable is determined depending on the target comfort state, wherein at least one vehicle-end device for changing the state variable is controlled so that a deviation in the actual state variable from the target state variable is minimized when the target comfort state deviates from the starting comfort state, wherein the at least one state variable is detected by a device carried by the user for detecting the at least one state variable.