Invention Grant
- Patent Title: Diaryl substituted 5,5-fused ring compounds as C5aR inhibitors
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Application No.: US16226898Application Date: 2018-12-20
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Publication No.: US10759807B2Publication Date: 2020-09-01
- Inventor: Pingchen Fan , Christopher W. Lange , Rebecca M. Lui , Viengkham Malathong , Venkat Reddy Mali , Sreenivas Punna , Rajinder Singh , Yibin Zeng , Penglie Zhang
- Applicant: CHEMOCENTRYX, INC.
- Applicant Address: US CA Mountain View
- Assignee: ChemoCentryx, Inc.
- Current Assignee: ChemoCentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo PC
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K9/00 ; A61K45/06 ; A61K31/4162 ; A61P35/00 ; A61P19/02 ; A61P11/00 ; A61P25/28 ; A61P37/06 ; A61P7/00 ; A61K9/10 ; A61K9/08

Abstract:
The present disclosure provides, inter alia, Compounds of Formula (I) or pharmaceutically acceptable salts thereof that are modulators of the C5a receptor. Also provided are pharmaceutical compositions and methods of use including the treatment of diseases or disorders involving pathologic activation from C5a and non-pharmaceutical applications.
Public/Granted literature
- US20190194208A1 DIARYL SUBSTITUTED 5,5-FUSED RING COMPOUNDS AS C5aR INHIBITORS Public/Granted day:2019-06-27
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