Invention Grant
- Patent Title: VMP-like sequences of pathogenic Borrelia species and strains
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Application No.: US16412913Application Date: 2019-05-15
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Publication No.: US10759833B2Publication Date: 2020-09-01
- Inventor: Steven J. Norris
- Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K39/02 ; A61K39/00 ; C07K14/20 ; G01N33/569 ; C07K17/08 ; C07K17/12 ; C08G69/48 ; G01N33/68
Abstract:
The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.
Public/Granted literature
- US20200040043A1 VMP-LIKE SEQUENCES OF PATHOGENIC BORRELIA SPECIES AND STRAINS Public/Granted day:2020-02-06
Information query
