Invention Grant
- Patent Title: JAM-C antibodies and methods for treatment of cancer
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Application No.: US15886802Application Date: 2018-02-01
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Publication No.: US10759857B2Publication Date: 2020-09-01
- Inventor: Beat Imhof , Christiane Ody , Thomas Matthes , Carmen Donate
- Applicant: Research Development Foundation
- Applicant Address: US NV Carson City
- Assignee: Research Development Foundation
- Current Assignee: Research Development Foundation
- Current Assignee Address: US NV Carson City
- Agency: Parker Highlander PLLC
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K45/06 ; C07K16/30 ; A61K47/68 ; G01N33/574 ; A61P35/00 ; A61K47/69 ; A61K39/00
Abstract:
A novel method to reduce B-cell lymphoma cell migration to and engraftment of the spleen in patients with JAM-C positive B-cell lymphomas is described. In certain aspects, a method for identifying and treating JAM-C positive B-cell lymphoma patients with anti-JAM-C antibodies is provided. Recombinant antibody molecules that specifically bind to JAM-C are also disclosed.
Public/Granted literature
- US20180171013A1 JAM-C ANTIBODIES AND METHODS FOR TREATMENT OF CANCER Public/Granted day:2018-06-21
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