The instant invention relates to a process for the encapsulation of a non-amine hydrophilic compound C, comprising the steps of: (E1) providing a reverse emulsion containing: an oil phase (O), comprising a curable mixture of isocyanate and polyalkyldiene hydroxylated or polyol dispersed in said oil phase, drops of an aqueous phase W1, containing: said non-amine hydrophilic compound C; and at least 5% by weight of a compound C carrying more than 2 amine groups; (E2) pouring the reverse emulsion of step (E1) in a second water phase W2 to make a multiple emulsion water/oil/water; and, then, (E3) curing into polyurethane all or part of the curable mixture contained in the oil phase.