Invention Grant
- Patent Title: CMV glycoproteins and recombinant vectors
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Application No.: US15827649Application Date: 2017-11-30
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Publication No.: US10760097B2Publication Date: 2020-09-01
- Inventor: Louis Picker , Klaus Früh , Scott G. Hansen
- Applicant: Oregon Health & Science University
- Applicant Address: US OR Portland
- Assignee: OREGON HEALTH & SCIENCE UNIVERSITY
- Current Assignee: OREGON HEALTH & SCIENCE UNIVERSITY
- Current Assignee Address: US OR Portland
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: C12N15/86
- IPC: C12N15/86 ; A61K39/12 ; C12N7/00 ; A61K39/00
Abstract:
Disclosed herein are recombinant CMV vectors which may comprise a heterologous antigen that can repeatedly infect an organism while inducing a CD8+ T cell response to immunodominant epitopes of the heterologous antigen. The CMV vector may comprise a deleterious mutation in the US11 glycoprotein or a homolog thereof.
Public/Granted literature
- US20190211356A1 CMV GLYCOPROTEINS AND RECOMBINANT VECTORS Public/Granted day:2019-07-11
Information query
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