A refrigeration unit may include a first compressor constructed and arranged to compress a first refrigerant, and a second compressor constructed and arranged to compress a second refrigerant. A first condenser of the refrigeration unit is operatively coupled to the first compressor, and a second condenser is operatively coupled to the second compressor. An evaporator of the refrigeration unit is constructed and arranged to flow the first and second refrigerants received from the respective first and second condensers for chilling a heat transfer fluid. A controller of the refrigeration unit includes a computer processor and a storage media for executing a pre-programmed algorithm for initialing the second compressor when a predetermined crossover frequency of the first compressor is reached as a system load increases.