This invention discloses a drive circuit for transmitting data signals on power wire, and such drive circuit comprises: a DC power module, a switching circuit module, a voltage division clamping circuit, a receiving module and a control circuit module; after the switching circuit module and the voltage division clamping circuit module are connected in parallel, one end of them is connected to one end of receiving module, and the other end is connected to one end of DC power module; the other end of receiving module is connected to the other end of DC power module; the control circuit module is connected to the switching circuit module, and controls the conduction and disconnection of switching circuit module; when the switching circuit module is conducted, the DC power module will apply a high voltage to the receiving module through the switching circuit module, and when the switching circuit module is disconnected, the DC power module will apply a low voltage to the receiving module through the voltage division clamping circuit module.