Invention Grant
- Patent Title: Stable nimodipine parenteral formulation
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Application No.: US16046476Application Date: 2018-07-26
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Publication No.: US10765671B2Publication Date: 2020-09-08
- Inventor: S. George Kottayil , Amresh Kumar , Prasanna Sunthankar , Vimal Kavuru
- Applicant: NORTIC HOLDINGS INC.
- Applicant Address: US NJ East Brunswick
- Assignee: NORTIC HOLDINGS INC.
- Current Assignee: NORTIC HOLDINGS INC.
- Current Assignee Address: US NJ East Brunswick
- Agency: Davidson, Davidson & Kappel, LLC
- Main IPC: A61K31/455
- IPC: A61K31/455 ; A61K31/4422 ; A61K47/10 ; A61K47/24 ; A61K47/26 ; A61K47/44 ; A61K9/00 ; A61K9/107

Abstract:
A nimodipine injection concentrate and diluted formulation comprises nimodipine (base or salt), an effective amount of a hydrophilic surfactant, and a pharmaceutically acceptable carrier for injection which is an aqueous solution, an organic solvent, an oil, or a cyclodextrin, such that the nimodipine is substantially contained in a concentrated injection solution, suspension, emulsion or complex as a micelle or a colloidal particle or an inclusion complex and the formulation is stable and clear. In certain embodiments, the hydrophilic surfactant is polysorbate 80.
Public/Granted literature
- US20180325886A1 STABLE NIMODIPINE PARENTERAL FORMULATION Public/Granted day:2018-11-15
Information query
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