A temperature regulating liquid crystal panel packaging box is provided, including a box body and a temperature regulator, the box body includes an accommodating part, the temperature regulator is arranged in the accommodating part to release or absorb heat as an outside temperature changes to keep an internal temperature of the box body balanced. In the liquid crystal panel packaging box, by disposing a temperature regulator on the periphery of the box body, when the outside temperature changes, the temperature regulator may spontaneously absorb heat or release heat to regulate the temperature inside the box body, thereby reducing the temperature difference between the inside and outside the box and preventing the water vapor in the air from condensing inside the box.