Invention Grant
- Patent Title: Morphinan derivatives for the treatment of neuropathic pain
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Application No.: US15569726Application Date: 2016-05-05
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Publication No.: US10766864B2Publication Date: 2020-09-08
- Inventor: Neel K. Anand , Natalia Aurrecoechea , Lin Cheng , Bo-Liang Deng , Donogh John Roger O'Mahony , YongQi Mu , Erik Krogh-Jespersen
- Applicant: Nektar Therapeutics
- Applicant Address: US CA San Francisco
- Assignee: Nektar Therapeutics
- Current Assignee: Nektar Therapeutics
- Current Assignee Address: US CA San Francisco
- Agent Jacqueline F. Mahoney
- International Application: PCT/US2016/030933 WO 20160505
- International Announcement: WO2016/182840 WO 20161117
- Main IPC: C07D221/28
- IPC: C07D221/28 ; C07D401/12 ; C07D417/12 ; C07D513/08 ; C07D407/12 ; A61P25/04 ; C07D407/04 ; C07D471/08
Abstract:
The present invention relates to compounds and their use as ligands for mu opioid receptors. Also included are methods for preparing the compounds and pharmaceutical compositions containing the compounds. In one or more embodiments of the invention, a compound according to Formula I is provided: and pharmaceutically acceptable salts thereof, wherein R1-R11 are as described herein.
Public/Granted literature
- US20180127375A1 MORPHINAN DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN Public/Granted day:2018-05-10
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