Invention Grant
- Patent Title: Triazoles for the treatment of demyelinating dieases
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Application No.: US16162835Application Date: 2018-10-17
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Publication No.: US10766869B2Publication Date: 2020-09-08
- Inventor: Robert J. Davies , Jingrong Cao , Meghan Elise Cockerill , Philip Noel Collier , Elisabeth Doyle , James Daniel Frantz , Huai Gao , Brian Anthony Goldman , Ronald Lee Grey, Jr. , Anne-Laure Grillot , Wenxin Gu , James A. Henderson , Raul Eduardo Krauss , Adrianne Lynn Kolpak , Yusheng Liao , Sanjay Shivayogi Magavi , David Messersmith , Albert Charles Pierce , Emanuele Perola , Elizabeth Jin-Sun Ryu , Joshua Syken , Jian Wang , Michael Paul DeNinno , Francois Maltais
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: VERTEX PHARMACEUTCALS INCORPORATED
- Current Assignee: VERTEX PHARMACEUTCALS INCORPORATED
- Current Assignee Address: US MA Boston
- Agency: Barnes & Thornburg LLP
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/4196 ; A61K31/454 ; A61K31/5377 ; A61P25/28 ; C07D249/14 ; C07D405/14 ; C07D401/04 ; C07D401/12 ; C07D403/04 ; C07D403/14 ; C07D405/12 ; A61K31/4439 ; A61K31/497 ; C07D403/12
Abstract:
The invention relates to triazole compounds of formula I and I′ or pharmaceutically acceptable salts thereof, useful as modulators of demyelinating diseases: The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention, methods of using the compositions and kits thereof in the treatment of various demyelinating and neurodegenerative diseases, including multiple sclerosis.
Public/Granted literature
- US20190185436A1 TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES Public/Granted day:2019-06-20
Information query
IPC分类:
