Invention Grant
- Patent Title: GLS1 inhibitors for treating disease
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Application No.: US16412050Application Date: 2019-05-14
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Publication No.: US10766892B2Publication Date: 2020-09-08
- Inventor: Maria Emilia Di Francesco , Philip Jones , Timothy Heffernan , Matthew M. Hamilton , Zhijun Kang , Michael J. Soth , Jason P. Burke , Kang Le , Christopher Lawrence Carroll , Wylie S. Palmer , Richard Lewis , Timothy McAfoos , Barbara Czako , Gang Liu , Jay Theroff , Zachary Herrera , Anne Yau
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Dennis A. Bennett; Cynthia Hathaway; John Desper
- Main IPC: C07D417/14
- IPC: C07D417/14 ; A61K31/4439 ; A61K45/06 ; C07D417/06 ; A61K31/433 ; C07D403/06 ; A61K31/501 ; C07D401/14 ; A61K31/454 ; A61K31/4192 ; C07D405/14 ; C07D403/14 ; A61K31/444 ; C07D493/08 ; A61K31/497
Abstract:
Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
Public/Granted literature
- US20190270736A1 GLS1 INHIBITORS FOR TREATING DISEASE Public/Granted day:2019-09-05
Information query
