Invention Grant
- Patent Title: Process and intermediates for the 6,7-alpha-epoxidation of steroid 4,6-dienes
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Application No.: US16302057Application Date: 2017-05-18
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Publication No.: US10766921B2Publication Date: 2020-09-08
- Inventor: Alexander Weymouth-Wilson , Zofia Komsta , Laura Wallis , Timothy Evans
- Applicant: NZP UK Limited
- Applicant Address: GB Bristol
- Assignee: NZP UK Limited
- Current Assignee: NZP UK Limited
- Current Assignee Address: GB Bristol
- Agency: Morgan, Lewis & Bockius LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@67c4c682
- International Application: PCT/GB2017/051389 WO 20170518
- International Announcement: WO2017/199036 WO 20171123
- Main IPC: C07J71/00
- IPC: C07J71/00 ; C07J9/00 ; C07J41/00 ; C07J43/00 ; C07J31/00 ; C07J17/00 ; C07J13/00 ; C07J51/00
Abstract:
The invention relates to a process for preparing a compound of general formula (Ia): wherein R2, Y, R4 and R5 are as defined herein, wherein the epoxidation is conducted using an oxidant and methyltrioxorhenium as a catalyst (MeReO3). The invention also relates to certain compounds per se. The compounds are intermediates in the synthesis of synthetic bile acids.
Public/Granted literature
- US20190309012A1 Process and Intermediates for the 6,7-Alpha-Epoxidation of Steroid 4,6-Dienes Public/Granted day:2019-10-10
Information query
