- Patent Title: Composition for autophagy inhibiting in cell, and pharmaceutical composition for preventing or treating tumor disease, or inhibiting anti-cancer agents resistance containing the same
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Application No.: US15780347Application Date: 2018-05-28
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Publication No.: US10766926B2Publication Date: 2020-09-08
- Inventor: Do Yong Jeon , Chang Hoon Moon , Ji Eun Jung
- Applicant: L-BASE CO., LTD
- Applicant Address: KR Seoul
- Assignee: L-BASE CO., LTD
- Current Assignee: L-BASE CO., LTD
- Current Assignee Address: KR Seoul
- Agency: Vorys, Sater, Seymour & Pease LLP
- Agent Mih Suhn Koh
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@36c5a7af
- International Application: PCT/KR2018/006023 WO 20180528
- International Announcement: WO2019/208868 WO 20191031
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K7/06 ; A61P35/00
Abstract:
Provided are a polypeptide having the activity of inhibiting autophagy in a cell, a composition for inhibiting autophagy in a cell, and particularly in a tumor cell, containing the polypeptide as an active ingredient, and a pharmaceutical composition containing the polypeptide, and more specifically, a composition for inhibiting autophagy in a cell containing a polypeptide inhibiting the control mechanism of autophagy as an active ingredient, and a pharmaceutical composition for preventing or treating a neoplastic disease or for inhibiting resistance to anticancer agents, containing the polypeptide.
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