- Patent Title: Fast-off rate serum albumin binding fibronectin type III domains
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Application No.: US15760413Application Date: 2016-09-22
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Publication No.: US10766946B2Publication Date: 2020-09-08
- Inventor: Stanley Richard Krystek, Jr. , Tracy S. Mitchell , Michael L. Gosselin , Dasa Lipovsek , Juhi Juneja
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- International Application: PCT/US2016/053183 WO 20160922
- International Announcement: WO2017/053617 WO 20170330
- Main IPC: C07K14/78
- IPC: C07K14/78 ; C07K14/765 ; C12N15/85
Abstract:
Provided herein are polypeptides which include tenth fibronectin type III domains (10Fn3) that binds to serum albumin. Also provided are fusion molecules comprising a serum albumin binding 10Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.
Public/Granted literature
- US20180258158A1 FAST-OFF RATE SERUM ALBUMIN BINDING FIBRONECTIN TYPE III DOMAINS Public/Granted day:2018-09-13
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