Invention Grant
- Patent Title: Anti-TGF-β antibodies and their use
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Application No.: US15875532Application Date: 2018-01-19
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Publication No.: US10766955B2Publication Date: 2020-09-08
- Inventor: Gary Shapiro , Kevin Brower , Patrick Finn , Richard C. Gregory , Rao Koduri , Feng Liu , Natalia Malkova , Parminder Mankoo , Jack R. Pollard , Huawei Qiu , Joachim Theilhaber , Christopher Winter , Marcella Yu
- Applicant: SANOFI
- Applicant Address: FR Paris
- Assignee: SANOFI
- Current Assignee: SANOFI
- Current Assignee Address: FR Paris
- Agency: Steptoe & Johnson LLP
- Agent Z. Ying Li; Mauricio Alvarez
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@3672ec1d
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61P35/00 ; C07K16/22 ; C07K16/30 ; C07K16/32 ; C07K16/28
Abstract:
The invention provides an improved pan-TGF-β antibody for treatment of conditions that are mediated by TGF-β, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.
Public/Granted literature
- US20180244763A1 ANTI-TGF-BETA ANTIBODIES AND THEIR USE Public/Granted day:2018-08-30
Information query
