Invention Grant
- Patent Title: Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes
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Application No.: US15481452Application Date: 2017-04-06
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Publication No.: US10767167B2Publication Date: 2020-09-08
- Inventor: Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut
- Applicant: INSTITUT PASTEUR , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
- Applicant Address: FR Paris FR Paris
- Assignee: INSTITUT PASTEUR,INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
- Current Assignee: INSTITUT PASTEUR,INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
- Current Assignee Address: FR Paris FR Paris
- Agency: Arrigo, Lee, Guttman & Mouta-Bellum LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1f163116
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N9/12 ; A61K38/00
Abstract:
This invention relates to the field of anticancer therapy, and to the identification of immunogenic peptides derived from the human telomerase reverse transcriptase (hTERT). The present invention relates to polynucleotides encoding hTERT epitopes restricted to MHC class I molecule, analogues thereof and polyepitopes containing such epitopes and/or analogues. Are also included in the present invention, vector and cell comprising such polynucleotides. The present invention also concerns composition comprising hTERT polypeptides, corresponding polynucleotides, vectors and cells, for use in the treatment and/or prevention of cancer.
Public/Granted literature
- US20170298328A1 POLYNUCLEOTIDES ENCODING MHC CLASS I-RESTRICTED HTERT EPITOPES, ANALOGUES THEREOF OR POLYEPITOPES Public/Granted day:2017-10-19
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