Invention Grant
- Patent Title: Method of preparing porcine circovirus type 2 capsid protein and pharmaceutical composition comprising same
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Application No.: US15778062Application Date: 2015-12-28
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Publication No.: US10767185B2Publication Date: 2020-09-08
- Inventor: Jiunn-Horng Lin , Zeng-Weng Chen , Jyh-Perng Wang , Tzu-Ting Peng , Huei-Yu Lee , Weng-Zeng Huang , Shih-Rong Wang , Cheng-Yao Yang
- Applicant: AGRICULTURAL TECHNOLOGY RESEARCH INSTITUTE
- Applicant Address: TW Hsinchu
- Assignee: AGRICULTURAL TECHNOLOGY RESEARCH INSTITUTE
- Current Assignee: AGRICULTURAL TECHNOLOGY RESEARCH INSTITUTE
- Current Assignee Address: TW Hsinchu
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/CN2015/099172 WO 20151228
- International Announcement: WO2017/113050 WO 20170706
- Main IPC: C12N15/63
- IPC: C12N15/63 ; C12N15/70 ; A61P31/20 ; A61K38/16 ; A61K47/42 ; A61K39/12 ; C07K14/57 ; A61K39/00 ; C07K14/56
Abstract:
The present invention provides a preparation method for PCV2 capsid protein and a pharmaceutical composition containing said capsid protein. The method of the present invention uses a novel arabinose-induced expression vector and thereby improves the synthesis efficiency of said PCV2 capsid protein. On the other hand, the present pharmaceutical composition combines said capsid protein and other favorable components at a proper ratio so that achieves excellent immune-inducing effects.
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